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. 2016 Jul 21;19(2):215–223. doi: 10.1038/gim.2016.87

Figure 2.

Figure 2

Example of interpretive scale to visualize a drug metabolism gene's phenotype. Phenotype frequencies were estimated using the equation describing Hardy-Weinberg equilibrium based on the allele frequencies published in the Clinical Pharmacogenetics Implementation Consortium guideline.17 For CYP2C19, phenotype frequencies differ substantially by ancestry. “Caucasian” includes those identified as European or North American in primary literature.