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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Small. 2016 Sep 27;12(46):6388–6397. doi: 10.1002/smll.201602263

Figure 5.

Figure 5

Porous structure and drug release behavior of the hybrid NCs. (a) N2 adsorption-desorption isotherm and (b) pore diameter distribution of Fe3O4@CDs@mSiO2@PTX@mSiO2 NCs. (c) HPLC analysis of initial PTX solution and residual PTX solution from the preparation of Fe3O4@CDs@mSiO2@PTX@mSiO2 NCs. (d) Release profiles of PTX from Fe3O4@CDs@mSiO2@PTX@mSiO2 NCs in PBS at 37°C, with or without of irradiation of NIR light. NIR was irradiated at 1.5 W cm−2 for 5 min each at predefined time points (6, 22, and 32 h). The inset in (d) is a schematic illustration of the release of PTX from Fe3O4@CDs@mSiO2@PTX@mSiO2 NCs.