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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Aliment Pharmacol Ther. 2016 Dec 8;45(3):381–390. doi: 10.1111/apt.13886

Table 1. Characteristics of included studies.

Authors Location Study Period, median follow-up (y) after TC-PI Number of patients with TC-PI Proportion of patients with known small bowel disease at time of surgery (%) Definition of clinical recurrence 5- and 10-year risk of clinical recurrence 5- and 10-year risk of surgical recurrence
Korelitz, 1972 New York, USA 1940-1970, NR 67 NR NR - -
Steinberg, 1974 Birmingham, UK 1942-1973, 9y 73 52 New-onset symptoms 20%, NR -
Weterman, 1976 Leuven, Belgium 1934-1972, 8.3y 16 NR NR - -
Vender, 1979 Connecticut, USA 1958-1974, 8.8y 34 62 NR 27%, 40% -
Goligher, 1985 Leeds, UK 1959-1984, 15y 162 NR NR NR, 60% -
Ritchie, 1990 London, UK 1952-1988, NR 182 NR NR 7%, 11% -
Harling, 1991 Copenhagen, Denmark 1964-1989, 7.7y 84 0 NR - 29%, NR
Heimann, 1993 New York, USA 1976-1989, 3y 37 NR New-onset symptoms, confirmed by imaging or endoscopy - -
Ho, 1995 New York, USA 1952-1984, 6.8y 182 64 NR - NR, 34%
Yamamoto, 2000 Birmingham, UK 1958-1997, 18.6y 103 36 New-onset symptoms, confirmed by imaging, - 13%, 17%
Ecker, 2001 Homburg, Germany NR, 5.4y 92 NR NR - 3%, 14%
Bernell, 2001 Huddinge, Sweden 1955-1989, 12.9y 89 NR New-onset symptoms, confirmed by imaging, endoscopy or need for re-initiation of IBD-related therapy 24%, 37% -
Fichera, 2005 Illinois, USA 1985-2003, 1.2y 76 0 NR - 9%, 20%
Onali, 2009 Rome, Italy 2001-2007 14 NR New-onset symptoms, confirmed by imaging, endoscopy - -
Amiot, 2011 Paris, France 1990-2005 55 58 New-onset symptoms, confirmed by imaging, endoscopy or need for re-initiation of IBD-related therapy 27%, 40% 10%, NR
Koriche, 2012 Paris, France 1973-2010 83 54 New-onset symptoms, with need for re-initiation or escalation of IBD-related therapy - -
Leal-Valdivieso, 2012 Barcelona, Spain - 16 37 NR - -
Lopez, 2014 Massachusetts, USA NR, 1.6y 73 35 New-onset symptoms, confirmed by imaging, endoscopy or histology 35%, NR -

Abbreviations: NR, not reported; y, years