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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Trends Biotechnol. 2016 Sep 2;35(2):172–183. doi: 10.1016/j.tibtech.2016.08.001

Figure I. Parenchymal and nonparenchymal cell types of the liver.

Figure I

Kupffer macrophages (KMs), hepatic stellate cells (HSCs), liver sinusoidal endothelial cells (LSECs), and biliary epithelial cells are the major nonparenchymal cells (NPCs) in the liver. By secreting the indicated molecules, these NPCs impact the phenotype of primary human hepatocytes (PHHs). Percentages represent the relative number of each cell type in the human liver. Adapted from [6].