Skip to main content
. 2016 Dec 21;198(3):1308–1319. doi: 10.4049/jimmunol.1600583

FIGURE 1.

FIGURE 1.

Inhibition of TLR-induced IKKα/β and ERK phosphorylation by BMS-986126. PBMCs were cultured with different concentrations of BMS-986126 and stimulated with either 100 ng/ml LPS (A) or 10 μg/ml LTA (B) for 20 min. Some groups were stimulated with 10 μg/ml gardiquimod for 30 min (C). Lysates were analyzed using the Sally Sue ProteinSimple system. The pIKKα/β and pERK bands were normalized to actin bands for each group. Percentage inhibition relative to the vehicle control is shown under each band. Cropped bands for pIKKα/β, pERK, and actin are shown. One representative experiment of two is shown.