Table I. Clinical data of study controls and patients.
| Healthy Controls (n = 46) (PBMC) | CHB (n = 69) (PBMC, ALT ≤60) | CHB (n = 44) (PBMC, ALT >60) | CHB Liver (n = 36) (Biopsy) | Control Liver (n = 9) (Perfusate) | |
|---|---|---|---|---|---|
| Age, y (mean ± SEM) | 32.4 ± 1.4 | 37.8 ± 1.3 | 37.1 ± 1.8 | 37.8 ± 1.7 | 42.2 ± 6.2 |
| Gender, female/male (%) | 56/44 | 36/64 | 52/48 | 33/67 | 44/56 |
| ALT IU/l [median (interquartile range)] | n.a. | 30.1 (21–37) | 142.4 (80–168) | 32.5 (24.3–76.8) | n.a. |
| HBeAg, positive/negative (%) | n.a. | 17.4/82.6 | 56.8/43.2 | 25/75 | n.a. |
| HBV DNA copies/ml [median (range)] | n.a. | 1.4 × 103 (20–3.2 × 108) | 4.1 × 106 (860–1.1 × 109) | 4.5 × 103 (20–6.5 × 105) | n.a. |
n.a., not applicable