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. 2017 Jan 23;7:8. doi: 10.3389/fonc.2017.00008

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Copyright © 2017 Wang, Mullins, Falchook, Lian, He, Shen, Dance, Lin, Sills, Das, Huang and Chera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Two different patients [(A), patient 7, and (B), patient 11] where PET/MRI substantially altered the primary GTV. Scans from left to right are the planning computed tomography (CT) scan (GTV-CT shown in red), magnetic resonance imaging (MRI) component of PET/MRI, and fused PET/MRI (GTV-PET/MRI shown in blue). Patient 7 (A) had a left tonsil primary. PET/MRI showed soft tissue encroachment to the uvula not delineated on CT, with a resultant increase in GTV size. Patient 11 (B) had a base of tongue primary. Though the planning CT-GTV included indeterminate soft tissue in the right base of tongue, PET/MRI showed tumor limited to the central base of tongue, with a resultant decrease in GTV size.