. 2017 Jan 13;7(1):e012633. doi: 10.1136/bmjopen-2016-012633

Table 2.

Distribution of second-order constructs across studies and CASP scores

Studies	Third-order constructs (developed by the synthesis team)
	Disruption and loss				Barriers		Facilitators
	Physical—the illness	Social—loss of a normal adolescent life	Social—increased dependence	Change in self	Problems with diagnosis	Uncertainty, disbelief and stigma	Credible illness narratives	Diagnosis, advice and increasing awareness	Supportive relationships	Personal growth and hope	Recovery	CASP scores 0–10
Jelbert et al⁴⁷		✓		✓	✓	✓		✓		✓	✓	10
Fisher and Crawley⁴⁸	✓	✓	✓	✓		✓	✓	✓	✓	✓		9
Hareide et al⁵⁴					✓		✓	✓		✓		8
Winger et al⁵¹	✓	✓		✓		✓				✓		7
Beasant et al⁵⁵								✓				9
Crix et al⁴⁶							✓					6*
Ashby et al⁴⁹							✓					3*
Patel⁵²	✓	✓	✓	✓		✓			✓		✓	10
Williams-Wilson⁵³	✓	✓	✓	✓	✓	✓	✓	✓	✓			10
Lombard⁵⁰	✓	✓	✓	✓					✓			6*

*Weaker quality study (CASP scores <6). Included in a sensitivity analysis by removing constructs from the synthesis.