Table 4. Diagnostic accuracy of Scys in predicting AKI at different time points.
| Time | Study number | Sensitivity (95% CI) | Specificity (95% CI) | DOR (95% CI) | I2 | AUROC (95% CI) |
|---|---|---|---|---|---|---|
| All settings 0 h | 12 | 0.79 (0.70, 0.86) | 0.82 (0.74, 0.88) | 17 (9, 35) | 92 | 0.88 (0.84, 0.90) |
| 1–12 h | 9 | 0.75 (0.70, 0.80) | 0.72 (0.68, 0.76) | 8 (5,12) | 0 | 0.80 (0.76, 0.83) |
| 24 h | 16 | 0.82 (0.69, 0.90) | 0.83 (0.76, 0.89) | 23 (9, 57) | 95 | 0.89 (0.86, 0.92) |
| 48 h | 7 | 0.76 (0.60, 0.88) | 0.87 (0.76, 0.93) | 21 (5, 58) | 94 | 0.89 (0.86, 0.92) |
| 1–6 h after cardiac surgery | 5 | 0.73 (0.65, 0.80) | 0.68 (0.62, 0.74) | 6 (4, 9) | 100 | 0.77 (0.73, 0.80) |
| 12–24 h after cardiac surgery | 6 | 0.85 (0.72, 0.92) | 0.80 (0.68, 0,89) | 23 (7, 77) | 7 | 0.90 (0.87, 0.92) |
Abbreviations: AKI, acute kidney injury; AUROC, the area under the receiver operating characteristic curve; DOR, diagnostic odds ratio; Scys, serum cystatin C.