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. 2017 Jan 18;8:14121. doi: 10.1038/ncomms14121

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Copyright © 2017, The Author(s)

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(a) By WES, global chromosomal gains (shown in red) and losses (shown in blue) across 97 NPC exomes from unique Asian NPC patients (rows) show recurrent arm-level CNV events. (b) Genome-wide view of copy number aberrations in 15 NPC tumours with WGS. Homozygous deletion regions containing cancer genes such as CDKN2A, FHIT, SMARCC1, CYLD are indicated. Amplification of 11q13 containing CCND1 is shown in HKNPC-075T and HKNPC-084T.