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. 2017 Jan 23;7:41082. doi: 10.1038/srep41082

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Zebrafish at 3 day post fertilization were exposed to indicated concentrations of PTS or Nom with or without 0.25 mM 6-OHDA for 4 days. Then zebrafish were collected and the locomotor activity of each group was monitored using the Viewpoint Zebrabox system; total distance traveled in 10 min was calculated. (A) Representative patterns of zebrafish locomotion traced from control and different treatment groups. (B) Statistical analysis of total distance moved of different treatment groups, eight fish larvae/group from three independent experiments. ^###P < 0.01 versus CTL group, **P < 0.01 versus 6-OHDA-treated group.