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. 2017 Jan 23;7:41003. doi: 10.1038/srep41003

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Copyright © 2017, The Author(s)

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(A) Domain structures of STAC1, STAC2, and STAC3. (B) STAC1 fails to show triad targeting in dysgenic myotubes expressing Ca_V1.1, but co-clusters with the channel in about half of the myotubes expressing Ca_V1.2 (51.8 ± 4.2%, N = 4, n = 120). Color overlay: 4X of blue rectangle. Scale bars: 10 μm and 5 μm. (C) Only STAC3 co-clusters with Ca_V1.1, while the three STAC proteins display different degrees of co-clustering with Ca_V1.2 (mean ± s.e.; N = 4, n = 120).