Figure 3.

Overall expression of arginase-1 (Arg-1) in the lung tissue treated with radiation and soy isoflavones (Rad + Soy) at 1, 4, and 12 weeks postradiation. Lungs tissue sections obtained from control (Con) mice and mice treated with radiation (Rad) or Rad + Soy at 1, 4, and 12 weeks after radiation were stained for Arg-1 by immunohistochemistry. An increase in staining of Arg-1⁺ cells was seen in the lungs treated with Rad + Soy, compared to Rad, which persisted at 12 weeks. All magnifications are at 40×.