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Type and extent of coding changes in genes implicated in 5-FC metabolisma
| Gene | Variable codons/total codon no. (%) | No. of heterozygous loci | No amino acid replacement
|
Amino acid replacements
|
|
|---|---|---|---|---|---|
| No. of synonymous replacements | No. of conservative replacements | No. of radical replacements | |||
| FCY21 | 8/514 (1.6) | 3 | 8 | 0 | 0 |
| FCY22 | 38/526 (7.2) | 37 | 25 | 5 | 8 |
| FCA1 | 11/150 (7.3) | 9 | 7 | 1 | 4 |
| FUR1 | 3/218 (1.4) | 3 | 2 | 0 | 1 |
Data for all 25 isolates.
