TABLE 2.
Parasitological and molecular tests of blood of dogs infected with the Berenice-78 and Y T. cruzi strains and treated with albaconazole or benznidazole
| Group | Therapeutic scheme (T. cruzi strain/drug/treatment time [days]) | No. of animals hemoculture positivea/total no. tested
|
No. of animals PCR positivea/total no. tested
|
No. of animals with positive test results posttreatment/total no. of animals tested (%) | ||
|---|---|---|---|---|---|---|
| 1 mob | 6 mob | 1 mo | 6 mo | |||
| 1 | Berenice-78/albaconazole/60 | 1/4 | 1/4 | 4/4 | 4/4 | 4/4 (100) |
| 2 | Berenice-78/albaconazole/90 | 2/4 | 1/4 | 4/4 | 4/4 | 4/4 (100) |
| 3 | Berenice-78/albaconazole/150 | 2/3 | 1/3 | 3/3 | 3/3 | 3/3 (100) |
| 4 | Berenice-78/benznidazole/60 | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 (0) |
| 5 | Berenice-78/untreated control | 3/6 | 3/6 | 6/6 | 6/6 | 6/6 (100) |
| 6 | Y/albaconazole/60 | 0/4 | 1/4 | 3/4 | 3/4 | 3/4 (75) |
| 7 | Y/albaconazole/90 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 (0) |
| 8 | Y/benznidazole/60 | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 (0) |
| 9 | Y/untreated control | 2/3 | 1/3 | 3/3 | 3/3 | 3/3 (100) |
a
Positive indicates positive by a at least one test.
b
Month after treatment.