Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Plasma indinavir PK parameters and threshold values for three different doses
| Dosea | No. (%) of patients with indicated toxicity threshold
|
||||
|---|---|---|---|---|---|
| Cmax of >10,000 ng/ml | C0h of >500 ng/ml | C12h of >500 ng/ml | C0h of <100 ng/ml | C12h of <100 ng/ml | |
| 800/100 | 1/5 (20) | 5/5 (100) | 2/5 (40) | 0/5 (0) | 0/5 (0) |
| 600/100 | 1/5 (20) | 2/5 (40) | 0/5 (0) | 0/5 (0) | 0/5 (0) |
| 400/100 | 0/5 (0) | 0/5 (0) | 0/5 (0) | 0/5 (0) | 0/5 (0) |
Doses (given twice daily) are given in milligrams of indinavir/milligrams of ritonavir.
