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PS-341 induces the production of reactive oxygen species in HNSCC cells and MEFs. (A, B, and C) UMSCC-23 cells, MEFs, and UMSCC-14A cells were treated with PS-341 or vehicle control for 4 h, respectively. After treatment, cells were harvested and incubated with the cell-permeable dye H2DCFDA. The reaction was analyzed by FACS.
