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. 2004 Nov;24(22):9948–9957. doi: 10.1128/MCB.24.22.9948-9957.2004

FIG. 4.

FIG. 4.

2D PFGE of TRFs from ALT and non-ALT cells. Total DNA (20 μg) was digested with HinfI/HaeIII and then separated by 2D PFGE. Telomeric material was detected by in-gel hybridization with a [γ-32P](CCCTAA)6 probe and was visualized using a PhosphorImager. The black and white arrows indicate linear- and circular-form DNA, respectively.