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. 2004 Nov;24(22):9848–9862. doi: 10.1128/MCB.24.22.9848-9862.2004

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Copyright © 2004, American Society for Microbiology

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FIG. 3. — Sensorimotor tests on knockout mice. HtrA2^+/+, HtrA2^+/−, and HtrA2^−/− mice were placed on a 60^o-inclined platform. (A) Percentages of mice that climbed to the top of the platform. Wild-type (+/+; n = 8); heterozygote (+/−; n = 20), and knockout (−/−; n = 16) littermates were compared. (B) Average elapsed times for mice to climb to the top of the platform. Data are means ± standard deviations of results from a minimum of eight trials. (C) Percentages of mice that remained on the platform for the full 60-s trial period. Wild-type (+/+; n = 8), heterozygote (+/−; n = 20), and knockout (−/−; n = 16) littermates were compared.

FIG. 3. — Sensorimotor tests on knockout mice. HtrA2^+/+, HtrA2^+/−, and HtrA2^−/− mice were placed on a 60^o-inclined platform. (A) Percentages of mice that climbed to the top of the platform. Wild-type (+/+; n = 8); heterozygote (+/−; n = 20), and knockout (−/−; n = 16) littermates were compared. (B) Average elapsed times for mice to climb to the top of the platform. Data are means ± standard deviations of results from a minimum of eight trials. (C) Percentages of mice that remained on the platform for the full 60-s trial period. Wild-type (+/+; n = 8), heterozygote (+/−; n = 20), and knockout (−/−; n = 16) littermates were compared.