TABLE 1.
Assessment of neuromuscular abnormalities in wild-type and HtrA2/Omi knockout mice by determining hind leg posture following suspension by the tail
Mouse HtrA2/Omi genotype | Posturea on day:
|
|||||||
---|---|---|---|---|---|---|---|---|
23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | |
+/+ and +/− | N | N | N | N | N | N | N | N |
−/− | N | N | A | A | A | A | A | A |
N, normal posture with extended hind limbs and digits; A, abnormal with retracted hind feed and clenched digits. Each data point is the result of analysis of at least three animals.