Table 1.

SSRI Clinical biosignature: potential moderators of the efficacy of treatment with SSRI vs. placebo with respect to change in HRSD from baseline to week 8. The 3rd column gives the -values for the interaction predictor-by-treatment term and the 4th column gives the effect size of the predictor as a moderator of treatment effect from a regression model with only that variable as a predictor in addition to treatment. The last two columns give the regression coefficients from models with all five baseline measures as predictors for treatment (placebo) and (SSRI) respectively

	Mean	St. dev.	Interaction	Effect	Reg. coefs
			p value	size
Anxiety	5.36	1.80	0.797	0.020	1.06	1.44
Anger attack	3.05	2.12	0.671	0.034	0.59	0.09
Suicide risk	5.42	2.37	0.155	0.113	1.00	0.38
Medical comorbidity score	2.01	2.78	0.092	0.140	0.11	0.58
Life pleasure score	33.17	5.51	0.065	0.148	0.20	0.04