Table 4.

The sensitivities, specificities, and PPV and NPV for (ECG) septal remodelling in classifying LMNA mutation carriers from the DCM controls, healthy controls or the combined control group of DCM controls and healthy controls

	Septal remodelling, N (%)	Current or previous AV block, flat P wave or septal remodelling, N (%)
LMNA mutation carriers	22 (81.5)	26 (96.3)
Healthy controls	0	0
DCM controls	16 (20.5)	32 (41.0)
LMNA vs DCM controls	Per cent	Per cent
Sensitivity	81.5	96.3
Specificity	79.5	59.0
PPV	57.9	44.8
NPV	92.5	97.9
LMNA vs healthy controls
Sensitivity	81.5	96.3
Specificity	100	100
PPV	100	100
NPV	80	95.2
LMNA vs DCM or healthy controls
Sensitivity	81.5	96.3
Specificity	83.7	67.3
PPV	57.9	44.8
NPV	94.3	98.5

DCM, dilated cardiomyopathy; NPV, negative predictive value; PPV, positive predictive value.