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. 2017 Jan 4;114(3):E317–E326. doi: 10.1073/pnas.1614684114

Fig. S7.

Fig. S7.

DUSP5 facilitates BRAFV600E-driven cell proliferation. WT and Dusp5 KO MEFs were infected with 3 pfu/nL of empty Ad, Ad HA-HRASQ61L, or Ad HA-BRAFV600E and either treated with 100 nM PD0325901 MEK inhibitor (PD) or coinfected using 0.3 pfu/nL Ad DUSP5-Myc for 24 h before 2-h pulse labeling with fluorescent EdU for assessment of proliferative index using HCM. Plots show the percentage of EdU-positive cells (% S-phase) in each condition ± SEM, n = 3–5. **P < 0.01 using one-way ANOVA and Dunnett's posttest comparing all columns to KO.