Table S1.

DNA sequences used in this work

Strand	Description	Sequence
Thiolated strands
1	AuNP-bound strand	5′TCC ACT CAT ACT CAG CAA (Spacer18*)2 SH 3′
2	AuNP-bound strand	5′TCA ACT ATT CCT ACC TAC (Spacer18)2 SH 3′
Linker strands
3	d1 linker for 1	5′(A-dT†) TTG CTG AGT ATG AGT GGA TTT ACT GAG CAG CAC TGA TTT T AAGGAAA 3′
4	d1 linker for 2	5′(A-dT) GTA GGT AGG AAT AGT TGA TTT ACT GAG CAG CAC TGA TTT T TTTCCTT 3′
5	d2 linker for 1	5′T TTG CTG AGT ATG AGT GGA (A-dT) TT ACT GAG CAG CAC TGA TTT T AAGGAAA 3′
6	d2 linker for 2	5′T GTA GGT AGG AAT AGT TGA (A-dT) TT ACT GAG CAG CAC TGA TTT T TTTCCTT 3′
7	d3 linker for 1	5′T TTG CTG AGT ATG AGT GGA TTT ACT GAG CAG CAC TGA TTT (A-dT) AAGGAAA 3′
8	d3 linker for 2	5′T GTA GGT AGG AAT AGT TGA TTT ACT GAG CAG CAC TGA TTT (A-dT) TTTCCTT 3′
9	Duplexer	5′AAT GAC TCG TCG TGA CTA AA 3′

^*“Spacer18” refers to the Spacer Phosphoramidite 18 manufactured by Glen Research.

^†“A-dT” refers to Amino-Modifier C6 dT manufactured by Glen Research.