Fig. S5.

CsA treatment does not affect cell viability in the absence of TRAIL. (A) Different concentrations of CsA (up to 40 µM) do not affect cell viability in A549 cells. (B) CsA enhances TRAIL-mediated cell death in A549 cells. Cells were preincubated with CsA (0-40 µM) for 30 min, followed by treatment with or without 100 ng/mL of TRAIL and assayed for cell viability. Reduction in cell viability (%) was calculated relative to control wells containing no ligand. All of the results are mean values ± SD (n = 3).