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Schematic diagram of Rcor2 gene targeting strategy. Mice with conditional Rcor2 alleles (floxed) were generated by inserting LoxP sites flanking exons 5–9. Exons are depicted as black rectangles and LoxP sites as white diamonds. HSVTK, herpes simplex virus thymidine kinase; PGKNEO, neomycin resistance gene driven by the phosphoglycerine kinase promoter.
