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ZIKV proteins induce cell death and cellular oxidative stress. ZIKV-induced cell death was measured 48 h after GI by Trypan blue (TB) staining (A) and the yeast live/dead assay (B), which was measured by FUN-1 staining 40–45 h after GI. (C) ZIKV induces oxidative stress, as indicated by DHE staining showing ROS expression. Images were taken 48 h after GI. (Scale bar, 10 μm.) BF, bright-field.
