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Schematics of the ventricular myocyte model. (A) Schematic plot of the ventricular myocyte model consisting of 64 × 32 × 16 CRUs. (B) The coupling between different compartments and CRUs. CYTO, cytosolic space; DS, dyadic space; JSR, junctional SR; NSR, network SR; SUB, submembrane space. (C) The four-state RyR model. (D) The Markov LCC model.
