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Antiplasmodial activity and toxicity assessment of tested compounds
| Compound | P. falciparum IC50 (μM) | MCF7 IC50 (μM) | T47D IC50 (μM) | SI for MCF7 | SI for T47D |
|---|---|---|---|---|---|
| M1 | 22.29 | 36.34 | 28.85 | 1.63 | 1.29 |
| M2 | ≥50 | - | - | - | - |
| M3 | 7.82 | 20.80 | 3.15 | 2.65 | 0.4 |
| M4 | ≥50 | - | - | - | - |
| M5 | 28.64 | 34.75 | 19.39 | 1.21 | 1.21 |
| M6 | 7.27 | 29.90 | 9.35 | 4.11 | 1.28 |
| M7 | 2.3 | 17.19 | 11.65 | 7.47 | 5.06 |
| M8 | 22.04 | 20.60 | 9.07 | 0.93 | 0.41 |
| M9 | 32.32 | 34.99 | 29.47 | 1.08 | 0.91 |
| M10 | 36.38 | 20.27 | 11.72 | 0.55 | 0.55 |
| M11 | ≥50 | - | - | - | - |
| CQ | 0.775 | - | - | - | - |
