Table 1.

Obstetric history

Pregnancy number (year)	Maternal age	Pregnancy result and gestation	Comments	Placenta
1 (2003)	24	Spontaneous miscarriage, 10 weeks	Expectant management	Not examined
2 (2004)	25	Termination of pregnancy, first trimester	Expectant management	Not examined
3 (2010)	31	Spontaneous miscarriage, 11 weeks	Surgically managed with dilation and curettage (D&C)	Initially reported as unremarkable. On review, the estimated involvement of the maternal space by macrophages was ∼50%
4 (2011)	32	Intrauterine fetal demise (IUFD), 20 weeks	Medical management with misoprostol. Spontaneous passage of fetus but required D&C for the placenta	Initially reported as unremarkable. On review, the estimated involvement of the maternal space by macrophages was ∼40%
5 (2012)	33	IUFD at 27 weeks of a female fetus weighing 345 g	Developed mild preeclampsia with severe fetal intrauterine growth restriction. Undergone induction of labour following IUFD	The placenta weighed 154 g and measured 120×90 mm by 20 mm in thickness. The cord was centrally inserted and non-coiled. Microscopically intervillous histiocytosis was associated with abundant perivillous fibrin deposition, and immature second trimester villi. The estimated involvement of the maternal space by macrophages was ∼30%
6 (2013)	34	Healthy baby boy weighting 2200 g, with Apgars of 9 and 10 at 1 and 5 min respectively, delivered by elective caesarean section at 34 weeks	Managed with prednisone, enoxaparin, calcium and aspirin. Close monitoring with regular growth scans. Baby's growth plateaued between 32–34 weeks	Placenta reported as unremarkable, although pathologist unaware of previous diagnosis. On review, the estimated involvement of the maternal space by macrophages was minimal at ∼5%. The placenta weighed 348 g