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. 2017 Jan 23;7:41404. doi: 10.1038/srep41404

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(A) mRNA expression level of DHCR24 in 91 EC tissues and 12 non-tumor tissues in the GEO database. (B) Differential mRNA expression level of DHCR24 in the histological grading of the GEO database. n, number of analyzed samples. (C) mRNA expression level of DHC24 in freshly frozen endometrial cancer tissues. (D) Representative IHC staining of DHCR24 in the tissue microarray (TMA) of endometrial cancer from histological Grade 1 to Grade 3 of EC specimens. Scale bar, 50 μm. (E) Score of the IHC stained in the TMA of EC. Distribution of DHCR24 in the cytoplasm was quantified in EC. Scoring was conducted based upon the percentage of positively stained cells: 0–10% scored 0; 10–35% scored 1; 36–70% scored 2; and more than 70% scored 3. (F) Overall survival Kaplan-Meier estimate of DHCR24 alterations in TCGA (DHCR24 alteration group: Red line, No DHCR24 alteration group: Blue line).