Figure 4.

Mitochondrial functional parameters in control human neuroblastoma (SHSY5Y) cells, in amyloid β (Aβ) incubated SHSY5Y cells, in SHSY5Y cells treated with curcumin and in SHSY5Y cells incubated with Aβ and then treated with Aβ and in SHSY5Y cells treated with curcumin and then incubated with Aβ (n=4). We analyzed mitochondrial functional data in two ways: (1) the control SHSY5Y cells were compared with the SHSY5Y cells treated with Aβ, curcumin, Aβ+cucumin and curcumin+Aβ and (2) Aβ incubated SHSY5Y cells were compared with Aβ+curcumin SHSY5Y cells and curcumin+Aβ treated cells. We performed statistical analysis using ANOVA following the Dunnett correction, for: (a) H₂O₂ production, (b) lipid peroxidation, (c) ATP levels, (d) cytochrome oxidase activity and (e) cell viability.