Table 3.
Diaphragm muscle fiber cross‐sectional areas in old mice (μmb)
| Animal (n) | Untreated | Vehicle‐Control | 7,8‐DHF | Mixed Linear Model P‐value | ||
|---|---|---|---|---|---|---|
| (n = 5) | (n = 6) | (n = 6) | Fiber Type effect | Treatment effect | Interaction | |
| Type Ia |
542.2 ± 61.6 (218) |
669.7 ± 62.4 (182) |
496.1 ± 62.6 (175) |
<0.001 | 0.180 | <0.001 |
| Type IIab |
579.6 ± 57.2 (1235) |
857.7 ± 57.3 (984) |
711.1 ± 57.3 (958) |
|||
| Type IIx and/or IIb |
793.7 ± 60.1 (321) |
859.2 ± 57.7 (737) |
888.8 ± 58.5 (482) |
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Data are least squares mean ± SE in μm2. The number of muscle fibers of each type are in parenthesis.
a
Significant main effect of fiber type; different than type IIa and type IIx and/or IIb fibers.
b
Significant main effect of fiber type; different than type IIx and/or IIb fibers.