Table 4.

The percentages of laboratories either meeting the UK guidelines for extended RAS testing, or indeed overtesting or undertesting

	Run 1 (n=99)	Run 2 (n=108)
Percentage of laboratories exactly following UK guidelines	6.1	25.9
Percentage of laboratories overtesting	19.2	10.2
Percentage of laboratories undertesting	68.7	55.6
Percentage of laboratories where the testing panel was undetermined	6	8.3
TOTAL percentage of laboratories testing at least in accordance with UK guidelines	25.3	36.1

Adding together the laboratories following the UK guidelines and those overtesting gives the total percentage of laboratories meeting or exceeding the minimum requirements. The UK guidelines suggest the following coverage: KRAS codons 12, 13, 59, 61, 117 and 146 in addition to NRAS codons 12, 13, 59 and 61.