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. 2016 Oct 20;66(1):89–96. doi: 10.1136/gutjnl-2015-311308

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Adjusted survival curves for patients treated in institutions with high research participation. It shows the cumulative survival for patients treated in institutions that have ≥16% participation in interventional clinical trials for 0, 3 or ≥4 years. At the scale of this graph the results for 1 and 2 years are superimposable over that for 0 years. The curves are highly significantly different and show that the separation occurs principally in the first year of follow-up. Survival is adjusted for primary procedure, index admission, Dukes’ stage, age, deprivation and Experimental Cancer Medicine Centre status.