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. 2016 Aug 5;102(1):91–96. doi: 10.1136/archdischild-2015-309381

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This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Diagnostic criteria for AKI. Both pRIFLE and KDIGO classification systems stratify AKI into levels of severity, determined by changes in serum creatinine (SCr)/estimated creatinine clearance (eCCl) and changes in urine output. AKI severity strata can be reached through fulfilling criteria for either changes in SCr/eCCl or changes in urine output. AKI, acute kidney injury; pRIFLE, paediatric Risk or renal dysfunction, Injury to the kidney, Failure of kidney function, Loss of kidney function, and End-stage renal disease. KDIGO, Kidney Disease: Improving Global Outcomes; RRT, renal replacement therapy; eGFR, estimated glomerular filtration rate.