Figure 2.

Renal angina threshold to identify children who may require evaluation with acute kidney injury (AKI) biomarkers. The graphs depict risk of AKI versus decrease in estimated creatinine clearance (eCCl) and percentage increase in fluid overload. There are three risk groups defined for the paediatric intensive care unit (PICU) population: very high risk (intubated plus the presence of at least one vasopressor or inotrope), high risk (history of solid organ or bone marrow transplant) and moderate risk (PICU admission). Less evidence of injury is required for higher risk groups to fulfil ‘renal angina’ criteria and further validation with AKI biomarkers is required. (Adapted from Basu et al¹⁷).