Table 1.
Baseline characteristics of REGARDS participants according to albumin to creatinine ratio
| ACR Category, mg/g | ||||
|---|---|---|---|---|
| Characteristics | ACR < 15 (n=20,167) |
ACR = 15– 30 (n=3,089) |
ACR >30 (n=4,040) |
P value |
| Age (years)±SD | 64±9 | 67±10 | 67±10 | <0.001 |
| Women n(%) | 11058 (55) | 1776 (58) | 2004 (50) | <0.001 |
| African American n(%) |
7617 (38) | 1254 (41) | 2069 (51) | <0.001 |
| Education <high school graduation n(%) |
2103 (10) | 470 (15) | 744 (18) | <0.001 |
| Income <$35,000† n(%) |
7770 (39) | 1448 (47) | 2085 (52) | <0.001 |
| Body mass index‡ (kg/m2)±SD |
29.0±5.9 | 29.5±6.6 | 30.3±6.7 | <0.001 |
| Systolic BP (mmHg)±SD |
125±15 | 131±18 | 135±19 | <0.001 |
| Diastolic BP (mm Hg)±SD |
76±9 | 78±10 | 79±11 | <0.001 |
| Lifestyle habits | ||||
| Current smoker n(%) |
2686 (13) | 457 (15) | 744 (19) | <0.001 |
| Exercise (none) n(%) |
6250 (31) | 1142 (38) | 1657 (42) | <0.001 |
| Comorbidities | ||||
| Coronary heart disease n(%) |
3031 (15) | 654 (21) | 1079 (27) | <0.001 |
| Diabetes n(%) | 3085 (15) | 872 (28) | 1691 (42) | <0.001 |
| Hypertension n(%) |
10789 (54) | 2111 (69) | 3124 (78) | <0.001 |
| Atrial fibrillation n(%) |
1505 (8) | 327 (11) | 496 (13) | <0.001 |
| ECG Variables | ||||
| QRS Interval (ms)±SD |
88±15 | 90±18 | 91±19 | <0.001 |
| Corrected QT interval (ms)±SD 406±23 |
410±25 | 410±25 | <0.001 | |
| Heart rate (beats per minute)±SD |
66±11 | 68±12 | 69±13 | <0.001 |
| Left ventricular hypertrophy n (%) |
1638 (8) | 368 (12) | 588 (15) | <0.001 |
| Laboratory Parameters | ||||
| Glomerular Filtration Rate, ml/min/1.73m2 | <0.001 | |||
| ≥90 n(%) | 9596 (48) | 1315 (43) | 1380 (34) | |
| 60–89 n(%) | 9044 (45) | 1384 (45) | 1590 (39) | |
| 45–59 n(%) | 1156 (6) | 279 (9) | 549 (14) | |
| <45 n(%) | 371 (2) | 111 (4) | 521 (13) | |
| Total cholesterol (mg/dL)±SD |
191±41 | 190±43 | 193±39 | <0.001 |
| HDL (mg/dL)±SD |
52±16 | 52±17 | 50±16 | <0.001 |
| Medications | ||||
| Statins n(%) | 5995 (30) | 1049 (34) | 1554 (39) | <0.001 |
|
Antihypertensives n(%) |
11030 (55) | 2087 (68) | 3059 (76) | <0.001 |
| ACEI/ARB n(%) |
6464 (32) | 1275 (41) | 2011 (50) | <0.001 |
| Digoxin n(%) | 350 (2) | 127 (4) | 199 (5) | <0.001 |
†
Indicates annual family income
‡
BMI was calculated on weight in kilograms divided by height in meters squared