Table 1.
The modified Kings College Criteria for transplantation13
| Category 1 | Aetiology: paracetamol poisoning: pH <7.25 >24 hours after overdose and after fluid resuscitation |
| Category 2 | Aetiology: paracetamol poisoning: coexisting PT >100 s or INR >6.5 s, and serum creatinine >300 µmol/L or anuria, and grade 3–4 encephalopathy |
| Category 3 | Aetiology: paracetamol poisoning: serum lactate >24 hours after overdose >3.5 mmol/L on admission or >3 mmol/L after fluid resuscitation |
| Category 4 | Aetiology: paracetamol poisoning: two of the three criteria from category 2 with clinical evidence of deterioration (eg, increased ICP, FiO2 >50%, increasing inotrope requirements) in the absence of clinical sepsis |
ICP, intra-cranial pressure; INR, International Normalised Ratio; PT, prothrombin time.