Table III.
Efflux Rates (k out) and Half-Lives (t 1/2) of Metabolites for TM-ADC-647
| Cell line | k out(h− 1) | t 1/2(h) |
|---|---|---|
| BT-474 | 0.009 ± 0.004 | 75.3 |
| NCI-N87 | 0.022 ± 0.009 | 31.7 |
| SK-BR-3 | 0.015 ± 0.006 | 45.3 |
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