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. 2016 Mar 7;18(3):746–756. doi: 10.1208/s12248-016-9895-0

Table I.

The Number of Sets of Clearances Leading to Precise Estimates of Kp uu and Clearances, with Different SD of Generated Systemic Data

SD of systemic data
0.297 (determined from observations) 0.0891 (30% of 0.297) 0.0297 (10% of 0.297)
Sets without producing numerical error 98 98 98
Sets with precise estimate of CL act 13 19 31
Sets with precise estimate of CL pass 16 20 39
Sets with precise estimate of CL met 4 7 12
Sets with precise prediction of Kp uu 12 27 40