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. 2017 Jan 23;12(1):e0170291. doi: 10.1371/journal.pone.0170291

Fig 5. Induction of SART3-specific T cells in HCC patients.

Fig 5

(A) Representative results of the cytotoxic T lymphocyte (CTL) assay. The results are shown as specific cytotoxic activity, which was calculated as follows: (cytotoxic activity in the presence of peptide)–(cytotoxic activity in the absence of peptide); findings were considered positive at > 10%. (B) CTL assays [effector-to-target (E/T) ratio of 50:1] were performed in 18 HCC patients. The results are also shown as specific cytotoxic activity. Solid bars show the results for one patient. (C) Cytotoxicity of SART3-specific T-cell lines derived from the peptide was also measured against hepatoma cell lines. The cytotoxicity was considered positive when it was higher than that against K562, which shows non-specific lysis (E/T ratio of 50:1). Representative results are shown.