Table 6. The mutated position in LHG IgG heavy chain CDR3 sequences (CARGSPFLDSW).

$\text{Vname}$	3'V-REGION	N	D-REGION	5'J-REGION	$\text{Jname}$	Dname	Vmut	Dmut	Jmut
IGHV4-30-2	tgtgc$\underset{\_}{\text{c}}$agag.a		ggt$\underset{\_}{\text{c}}$g$\underset{\_}{\text{c}}$$\underset{\_}{\text{c}}$a$\underset{\_}{\text{t}}$tcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	1	4	1
IGHV4-30-4	tgtgccagag.		ggt$\underset{\_}{\text{c}}$g$\underset{\_}{\text{c}}$$\underset{\_}{\text{c}}$a$\underset{\_}{\text{t}}$tcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	0	4	1
IGHV4-31	tgtgc$\underset{\_}{\text{c}}$agag.		ggtcgccattcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	1	4	1
IGHV4-34	tgtgc$\underset{\_}{\text{c}}$agagg	gtc	……gc$\underset{\_}{\text{c}}$attcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD2-21	1	1	1
IGHV4-59	tgtgc$\underset{\_}{\text{c}}$agag.		ggt$\underset{\_}{\text{c}}$g$\underset{\_}{\text{c}}$$\underset{\_}{\text{c}}$a$\underset{\_}{\text{t}}$tcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	1	4	1
IGHV4-61	tgtgccagag.		ggt$\underset{\_}{\text{c}}$g$\underset{\_}{\text{c}}$$\underset{\_}{\text{c}}$a$\underset{\_}{\text{t}}$tcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	0	4	1
IGHV4-61	tgtgc$\underset{\_}{\text{c}}$aga.	g	ggt$\underset{\_}{\text{c}}$g$\underset{\_}{\text{c}}$$\underset{\_}{\text{c}}$a$\underset{\_}{\text{t}}$tcc	ttgact$\underset{\_}{\text{c}}$ctgg	IGHJ4	IGHD4-23	1	4	1

^a Red bases indicate the mutate bases in CDR3 region.