Table 2. Comparison of changes in retinal nerve fiber layer thickness during 6-month follow up period in eyes with non-proliferative diabetic retinopathy with or without diabetic macular edema.
| Characteristic | Group I (DME) | Group II (No DME) | ||
|---|---|---|---|---|
| Baseline (A) | At 6 M. (B) | Baseline (A) | At 6 M. (B) | |
| Total RNFL thickness (μm) | 126.4 ± 34.7 | 117.6 ± 28.8 | 100.7 ± 10.0 | 102.1 ± 12.1 |
| P valuesa | PA-B < 0.001 | PA-B = 0.079 | ||
| Temporal RNFL thickness (μm) | 117.1 ± 43.3 | 101.6 ± 40.8 | 81.2 ± 13.8 | 83.0 ± 15.5 |
| P valuesa | PA-B < 0.001 | PA-B = 0.036 | ||
| Superior RNFL thickness (μm) | 150.0 ± 53.4 | 140.5 ± 34.2 | 122.8 ± 19.3 | 124.2 ± 20.2 |
| P valuesa | PA-B = 0.068 | PA-B = 0.172 | ||
| Nasal RNFL thickness (μm) | 87.6 ± 22.1 | 84.2 ± 23.7 | 70.8 ± 11.2 | 71.9 ± 18.9 |
| P valuesa | PA-B = 0.117 | PA-B = 0.426 | ||
| Inferior RNFL thickness (μm) | 150.8 ± 35.9 | 144.2 ± 33.9 | 127.9 ± 17.6 | 129.2 ± 18.6 |
| P valuesa | PA-B = < 0.001 | PA-B = 0.159 | ||
aPaired T-test;
DME = diabetic macular edema; M. = months; RNFL = retinal nerve fiber layer