Table 5. Comparison of average changes of adjusted retinal nerve fiber layer thickness Index during 6-month follow up period in eyes with non-proliferative diabetic retinopathy with or without diabetic macular edema.
| Characteristic | Group I (DME) | Group II (No DME) | ||
|---|---|---|---|---|
| Baseline (A) | At 6 M. (B) | Baseline (A) | At 6 M. (B) | |
| Number of eyes | 50 | 50 | 90 | 90 |
| Average of Total RNFL thickness Index | 99.5 ± 15.0 | 98.4 ± 14.8 | 104.5 ± 13.6 | 103.0 ± 13.4 |
| P valuesa | PA-B = 0.593 | PA-B = 0.101 | ||
| Average of Temporal RNFL thickness Index | 89.9 ± 14.8 | 82.6 ± 16.8 | 84.2 ± 16.6 | 83.7 ± 16.5 |
| P valuesa | PA-B < 0.001 | PA-B = 0.460 | ||
| Average of Superior RNFL thickness Index | 117.8 ± 23.5 | 118.4 ± 22.8 | 127.4.0 ± 22.5 | 125.6 ± 22.7 |
| P valuesa | PA-B = 0.787 | PA-B = 0.170 | ||
| Average of Nasal RNFL thickness Index | 69.4 ± 12.5 | 70.7 ± 15.7 | 73.5 ± 13.4 | 72.5 ± 17.2 |
| P valuesa | PA-B = 0.626 | PA-B = 0.404 | ||
| Average of Inferior RNFL thickness Index | 120.9 ± 25.9 | 122.2 ± 25.1 | 132.6 ± 21.3 | 130.4 ± 21.0 |
| P valuesa | PA-B = 0.612 | PA-B = 0.051 | ||
aPaired T-test, p value is less than 0.01, it was considered to be statistically significant;
DME = diabetic macular edema; M. = months; RNFL = retinal nerve fiber layer