Table 1.
Characteristics | 30–49 (n = 70) | 50–90+ (n = 420) |
---|---|---|
Demographics | ||
Age, years, mean (SD) [min, max] | 40 (6) [30, 49] | 72 (10) [52, 94] |
Male gender, no. (%) | 36 (51) | 228 (54) |
Education, years, mean (SD) [min, max] | 16 (2) [12, 20] | 15 (2) [7, 20] |
APOE ε4 positive, no. (%) | 5 (19)∗ | 114 (27) |
Biomarker outcomes | ||
PiB, SUVR, mean (SD) [min, max] | 1.20 (0.05) [1.10, 1.35] | 1.47 (0.33) [1.12, 3.08] |
Abnormal PiB (>1.4), no. (%) | 0 (0) | 154 (37) |
Cognition | ||
Short test of mental status score, mean (SD) [min, max] | 37 (2) [32, 38] | 36 (2) [27, 38] |
Abbreviations: SD, standard deviation; PiB, Pittsburgh compound B; SUVR, standardized uptake value ratio.
Several missing APOE genotype.