Table II.
Insect Mitochondria | Mammalian Muscle Mitochondria** | |||
---|---|---|---|---|
Substrate | House fly flight muscle | Locust flight muscle | ASE cell (this study) | |
Glycerophosphate | 25 | ~1 | 1.4 | 0.1 – 1.0 |
Pyruvate + Malate | 25 | ~ 1.4 | 0.8 | 1 – 3 |
Ketoglutarate | 0.7 | 0.4 | 0.8 | 0.7–2 |
Octanoylcarnitine† | NA | 1.1 | 0.7 | 1–2 |
Succinate | 1 | 0.3 | 0.6 | 0.2 – 2 |
Substrate preference was calculated as the ratio of oxygen uptake with the indicated substrate and with glutamate. Values for house fly and locust were calculated from [24, 66].
Data for pigeon breast muscle, human skeletal muscle, and rat skeletal muscle were obtained from our lab (rat and human skeletal muscle) and compiled from [67–70] .
Data for locust were obtained with palmitoylcarnitine only. Mammalian data represent an average using palmitoylcarnitine and butyrylcarnitine. NA, not available.