Table 1.
Descriptive statistics for output measures from dynamic susceptibility contrast (DSC) and arterial spin labelling (ASL) within both tumour and healthy tissue regions of interest (ROIs). Tumours have been categorized according to tumour types across all samples
| Tumour classification | Number of patients (N) | DSC |
ASL |
ASL VC |
|||||
|---|---|---|---|---|---|---|---|---|---|
| DT (ms) | MTT (ms) | rCBV (ml/1000 ml) | rCBF (ml/100 ml min−1) | CBF (ml/100 ml min−1) | AAT (ms) | CBF (ml/100ml min−1) | AAT (ms) | ||
| Low grade (grades 1 and 2) | |||||||||
| Gliomas | 18 | 130 (SD: 148) | 317 (SD: 179) | 140 (SD: 139) | 167 (SD: 172) | 87 (SD: 83) | 819 (SD: 272) | 52 (SD: 44) | 1086 (SD: 315) |
| Choroid plexus papilloma | 1 | 91 | 1457 | 327 (SD: 126) | 161 | 72 | 346 | 43 | 626 |
| Pineal germ-cell tumour | 1 | 212 | 712 | 83 (SD: 100) | 66 | 28 | 1367 | No data | No data |
| High grade (3 and 4) | |||||||||
| Medulloblastoma | 2 | 196 (SD: 23) | 572 (SD: 265) | 550 (SD: 25) | 36 | 111 (SD: 16) | 655 (SD: 131) | 55 (SD: 4) | 920 (SD: 13) |
| PNET | 1 | 275 | 938 | 161.09 | 96 | 43 | 935 | 54 | 1178 |
| Anaplastic astrocytoma (intraoperative example) | 1 | 119 | 633 | 91 | 104 | 104 | 826 | 111 | 866 |
| Healthy tissue | |||||||||
| Control ROI from the group of patients with only glioma | 18 | 143 (SD: 179) | 497 (SD: 94) | 244 (SD: 377) | 261 (SD: 293) | 75 (SD: 54) | 811 (SD: 288) | 40 (SD: 22) | 1049 (SD: 319) |
| t-test between control and tumour ROI from the group of patients with only glioma (p-value) | 18 | 0.6 | 0.0009 | 0.268 | 0.001 | 0.6 | 0.9 | 0.1 | 0.7 |
AAT, arterial arrival time; CBF, cerebral blood flow; DT, delay time; MTT, mean transit time; PNET, primitive neuroectodermal tumours; rCBF, relative cerebral blood flow; rCBV, relative cerebral blood volume; SD, standard deviation; VC, vascular crushers.