Table 3.
Showing the comparative evaluation of acute toxicities in the two arms
| Toxicity | Subtypes | Grade | Arm A | Arm B | p-value |
|---|---|---|---|---|---|
| Haematological | Anaemia | Grade 1/2 | 0 | 1 | 0.99 |
| Grade ≥3 | 0 | 0 | – | ||
| Neutropaenia | Grade 1/2 | 0 | 1 | 0.99 | |
| Grade ≥3 | 1 | 1 | 0.99 | ||
| Thrombocytopenia | Grade 1/2 | 1 | 2 | 0.87 | |
| Grade ≥3 | 1 | 0 | 0.99 | ||
| Non-haematological | Skin reactions | Grade 1/2 | 6 | 1 | 0.04 |
| Grade ≥3 | 1 | 0 | 0.99 | ||
| Anorexia | Grade 1/2 | 7 | 9 | 0.63 | |
| Grade ≥3 | 0 | 1 | 0.99 | ||
| Mucositis | Grade 1/2 | 4 | 1 | 0.07 | |
| Grade ≥3 | 0 | 0 | – | ||
| Laryngitis | Grade 1/2 | 3 | 2 | 0.99 | |
| Grade ≥3 | 0 | 0 | – | ||
| Pharyngitis/oesophagitis | Grade 1/2 | 7 | 10 | 0.83 | |
| Grade ≥3 | 3 | 1 | 0.05 | ||
| Pneumonitis | Grade 1/2 | 6 | 3 | 0.26 | |
| Grade ≥3 | 1 | 0 | 0.99 | ||
| Peripheral neuropathy | Grade 1/2 | 4 | 4 | 0.99 | |
| Grade ≥3 | 2 | 2 | 0.99 | ||
| Hyponatraemia | Grade 1/2 | 0 | 0 | – | |
| Grade ≥3 | 1 | 0 | 0.99 |