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. 2016 Apr 19;89(1062):20160009. doi: 10.1259/bjr.20160009

Table 2.

Dose to avoidance structures using volumetric-modulated arc therapy (VMAT) vs split-field intensity-modulated radiation therapy (SF-IMRT). There was a statistically significant decrease in maximum (max) dose to the arytenoids and mean dose to the oesophagus. The two techniques were otherwise equivalent

Avoidance structure VMAT SF-IMRT p-values
Glottic larynx 20.1 Gy (mean) 19.5 Gy (mean) 0.65
Supraglottic larynx 39.6 Gy (mean) 40.9 Gy (mean) 0.67
Pharyngeal constrictors 46.6 Gy (mean) 46.9 Gy (mean) 0.50
Brachial plexus 64.2 Gy (max) 67.2 Gy (max) 0.37a
15.2% (V60) 12.8% (V60) 0.64
Arytenoids 23.8 Gy (max) 46.7 Gy (max) <0.001
Oesophagus 24.6 Gy (mean) 39.7 Gy (mean) <0.001

V60, volume receiving over 60 Gy.

p-values are in bold when p < 0.05.

a

Denotes statistically significant calculations at a biologically equivalent dose in 2 Gy fraction were performed.